Genetic diversity of Sub-Saharan Africa revealed

Genetic diversity of Sub-Saharan Africa revealed

BBC News
2014-12-04

Rebecca Morelle, Science Correspondent

Scientists have completed a comprehensive study of genetic diversity in Sub-Saharan Africa.

The African Genome Variation Project analysed the DNA of 1,800 people living across the continent.

The data is helping scientists to understand how susceptibility to disease varies across the region and has provided more insight into how populations have moved within Africa.

The research is published in the journal Nature.

Until now, most studies examining genetic risk factors for disease have focused on Europe. Little has been known about Africa, the most genetically diverse region in the world.

Dr Manj Sandhu, from the Wellcome Trust Sanger Institute and the University of Cambridge, said: “We originally set out to look at chronic diseases in Africa, and one strategy to understand the causes of those diseases is to look at the underlying genetic susceptibility.

“But to do that, you need a pretty good grasp of the variation in genomes across the region, but we realised that information wasn’t available.”…

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